Autonomic Imbalance and the HypthalamusAutonomic Imbalance and the Hypothalamus was first published in 1957. Fundamental alterations in the reactivity of autonomically innervated structures frequently have been observed in physiological tests as well as under clinical conditions. However, the mechanism of these alterations and the changes in the reactivity of the central structures of the autonomic nervous system that are their most frequent site of action had not been subjected to